Archive

The pharmaceutical companies mentioned below, in collaboration with South African Health Products Regulatory Authority (SAHPRA), wish to inform you of the class related cerebrovascular adverse events reported with the use of tyrosine kinase inhibitor (TKI) containing medicines. The Professional Information (PI) and Patient Information Leaflet...

The pharmaceutical companies mentioned below, in collaboration with South African Health Products Regulatory Authority (SAHPRA), wish to inform you of the risk of dopamine dysregulation syndrome (DDS) associated with the chronic use of dopaminergic medicines used for the treatment of Parkinson’s disease. The Professional Information...

The South African Health Products Regulatory Authority (SAHPRA) wishes to alert healthcare professionals about the risk of serious heart problems, seizures, coma and death associated with the use of high doses of diphenhydramine-containing medicines. An online challenge known as “the Benadryl Challenge” has recently been...

Pharmacare, in consultation with the South African Health Products Regulatory Authority (SAHPRA) would like to warn healthcare professionals about an increase of adverse events/side effects associated with the introduction of Eltroxin New Formulation® and a call for therapeutic drug monitoring in patients using or switched...

In collaboration with the South African Health Products Regulatory Authority (SAHPRA), the below listed companies would like to inform you of an increased risk of subclinical acute nephritis associated with the use of PPIs leading to chronic renal inflammation and reduced renal function....